To describe the real-world effectiveness of amlodipine add-on therapy for hypertensive patients receiving valsartan. Methods. Retrospective cohort study based on USA electronic medical records. The study population included hypertensive patients who, between January 1998 and December 2005, were receiving valsartan and subsequently initiated add-on therapy with amlodipine. Change in systolic blood pressure (SBP)/diastolic blood pressure (DBP), and attainment of goal SBP/DBP (i.e.v140/90 mmHg), were examined based on last available reading prior to day 180 following initiation of amlodipine.

本文来自Weycker, Derek, Keskinaslan, Abdulkadir, Levy, Drew Griffin, Edelsberg, John, Kartashov, Alex and Oster, Gerry(2008)'Effectiveness of add-on therapy with amlodipine in hypertensive patients receiving valsartan',Blood Pressure,17:4,5-12